Brymill Cryogenic Systems

Brymill Cryogenic Systems builds the cryosurgical devices dermatologists, podiatrists, and primary care clinicians reach for when they need controlled, targeted tissue freezing in the exam room. The company's liquid nitrogen sprayers have become a clinical standard for treating warts, skin tags, actinic keratoses, and other benign and premalignant lesions — delivering a precise cold spray without the mess or unpredictability of cotton-tip application.

At the center of this collection is the CRY-AC handheld cryospray device, offered here in two tank capacities. The 10 oz. CRY-AC (B-800), at 8.5 inches tall, is the lighter, more maneuverable option well suited to shorter procedure lists and clinicians who want an instrument that stays comfortable through a full day of treatments. The 16 oz. CRY-AC (B-700), standing 11.25 inches, holds more liquid nitrogen per fill — meaning fewer refills across a busy schedule and less interruption during back-to-back procedures.

Both devices use interchangeable spray tips and probes (sold separately) so you can dial the freeze zone to the lesion, whether that's a pinpoint plantar wart or a broader field of keratoses. The trigger-controlled spray gives the operator moment-to-moment command over freeze depth and duration, which is what separates a professional cryosurgical unit from over-the-counter freezing kits. The insulated tanks are self-pressurizing, so once filled with liquid nitrogen they're ready to use without external gas lines or power.

Choosing between the two usually comes down to volume: high-throughput dermatology and podiatry practices tend toward the 16 oz. unit, while satellite clinics, mobile providers, and lower-volume offices often prefer the balance and portability of the 10 oz. Both are refillable, durable, and designed for years of repeatable clinical use.