Cortizone 10 Anti-Itch & Hydrocortisone Creams

When itching won't quit — from eczema flare-ups, insect bites, poison ivy, or general skin irritation — Cortizone 10 delivers maximum-strength relief with 1% hydrocortisone, the highest concentration available without a prescription. This collection brings together fast-acting formulas built to calm inflammation, stop the itch-scratch cycle, and support irritated skin as it recovers.

The Cortizone-10 Itch Relief Cream (1 oz.) is the go-to for everyday itch emergencies — a compact tube of 1% hydrocortisone that works quickly on rashes, allergic reactions, and bug bites. For chronic, stubborn dryness and eczema, the Cortizone 10 Intensive Healing Eczema Lotion (3.5 oz.) pairs maximum-strength hydrocortisone with skin-nourishing ingredients to soothe the itch while helping restore the skin barrier over repeated use.

A common question: how often can you use it? Hydrocortisone 1% products are typically applied up to three or four times daily for short-term relief — usually no more than seven days unless directed by a doctor. If irritation persists beyond a week or worsens, that's the signal to check in with a healthcare provider rather than continuing to self-treat. Cortizone 10 is intended for external use only and should be kept away from the eyes.

Because it's fragrance-choice-driven and stocked in both cream and lotion formats, buyers can match the product to the problem: a cream for spot-treating bites and localized rashes, a lotion for spreading over larger eczema-prone areas like arms and legs. Keep one in the medicine cabinet and one in a bag or first-aid kit — itching rarely waits for a convenient moment.

Cortizone 10 is part of our broader 10 Series of trusted over-the-counter health essentials.