LMX4 Topical Pain Relief Cream

LMX4 is a fast-acting topical anesthetic cream from Ferndale Laboratories, formulated with 4% lidocaine to temporarily numb the skin and relieve minor pain, itching, and discomfort. It's a go-to for anyone facing a needle stick, minor burn, insect bite, or skin irritation who wants to take the sting out before it starts.

The active ingredient works by blocking nerve signals in the treated area, and its liposomal delivery helps the lidocaine absorb efficiently for reliable onset. Many patients and clinicians apply it about 20–30 minutes before a procedure such as an injection, IV insertion, or minor dermatological treatment — making it popular in both clinical settings and at home for those managing needle anxiety in children and adults alike.

This collection carries two tube sizes so you can match the amount to how you'll use it:

• LMX 4 Cream, 0.17 oz. — a compact size ideal for a single application site or occasional use, easy to keep in a first-aid kit or bag.
• LMX 4 Cream, 1.05 oz. — a larger tube better suited to repeat use, larger areas, or households and facilities that reach for it regularly.

Both are the same 4% strength Ferndale formula; the choice simply comes down to how often you'll use it and how much surface area you need to cover. Because it's an over-the-counter external analgesic, follow the label directions on frequency and coverage, and check with a clinician before use on broken skin or on young children.

For more options in numbing and pain management, browse our full Pain Relief selection, or explore related Topical Pain Relief products. You can also visit the Honest Medical homepage for the complete catalog.