Orthopedic Pharmaceuticals Orthogel Cold Therapy is a topical analgesic designed to provide fast, long-lasting relief from a variety of pain conditions. This formula utilizes a unique blend of natural ingredients, including Ilex, Aloe Vera, Vitamin E, Boswellia Serrata, and MSM, to penetrate deep into joints and muscles. Orthogel is ideal for individuals suffering from sports injuries, work-related injuries, arthritis, and other musculoskeletal pain. Its non-greasy, non-staining formula is easy to apply and can be used before and after physical activity to soothe and protect.