Pepcid AC & Pepcid Complete Heartburn Relief

Pepcid is one of the most recognized names in acid reducer relief, trusted for controlling the heartburn, acid indigestion, and sour stomach that follow certain foods or drinks. Its active ingredient, famotidine, is an H2 blocker that reduces the stomach acid your body produces — so instead of just neutralizing acid after the burn starts, it helps prevent symptoms before they happen and keeps them at bay for hours.

This collection covers both original-strength single-action tablets and dual-action formulas. Pepcid AC Original Strength Tablets deliver 10 mg of famotidine per tablet and are available in 30-count bottles, 50-count boxes, and 90-count boxes — the larger counts make sense for households or facilities managing frequent, predictable heartburn, while a single bottle suits occasional use. Bulk cases of 36 bottles are on hand for pharmacies, clinics, and long-term care settings that stock at volume.

Pepcid Complete takes a two-pronged approach in a single chewable tablet: famotidine to reduce acid production plus calcium carbonate and magnesium hydroxide antacids that neutralize existing acid on contact. That combination means fast relief within minutes and lasting control — a good fit when you want both immediate comfort and prevention. It comes in 25-count bottles, individually or by the 36-bottle case.

Which one is right depends on timing. If you know a spicy meal or late dinner tends to trigger symptoms, taking Pepcid AC beforehand helps head off the burn. If heartburn has already set in, Pepcid Complete's antacid component works faster. Both are for adults and children 12 and older, and neither should be used for more than the label-directed period without checking with a clinician.

For related self-care and stomach relief options, browse our full OTC Medications selection.