SANTYL Enzymatic Debriding Ointment

When necrotic tissue and slough stand in the way of healing, clinicians reach for SANTYL. As the only FDA-approved collagenase enzymatic debriding agent, it works selectively to break down dead tissue in chronic wounds and severe burns while leaving healthy granulation tissue undisturbed. For wound care nurses, long-term care facilities, and home health providers, that selectivity is the whole point: debridement happens continuously without the sharp instruments, repeat procedures, or collateral damage that other methods can bring.

Buyers searching for SANTYL usually already know what it does — their real questions are about application and stocking. It's indicated for debriding chronic dermal ulcers, including pressure injuries and diabetic foot ulcers, and severely burned areas. Because collagenase is enzymatically active, application details matter: it's typically applied once daily to the wound bed, and certain antiseptics and heavy-metal compounds (such as those containing silver, iodine, or mercury) can reduce its effectiveness, so wound cleansing choices should account for that. Refrigeration isn't required, but proper storage per the labeling protects potency.

SANTYL is a prescription product, and facilities managing wound care programs value a dependable supply so treatment protocols aren't interrupted mid-course of therapy. Consistent availability keeps daily dressing changes on schedule, which is central to moving a stalled wound toward closure.

SANTYL is one part of a broader approach to advanced wound management. Explore complementary dressings, cleansers, and skin protectants in our Wound Care collection to build a complete debridement and healing protocol.