Similac for Spit-Up is a nutritionally complete formula specially formulated with rice starch and clinically shown to reduce spit-up in healthy infants by 54% (reduced frequency among 2 month old healthy infants compared to a standard milk-based. This unique formula features OptiGRO (an exclusive blend of DHA, Lutein, and Vitamin E - special nutrients found in breast milk that are important for helping support baby's brain and eye development), and Similac is the first infant formula brand with no artificial growth hormone (no significant difference has been shown between milk derived from rbST-treated and non-rbST-treated cows).