The biggest choice is how many infusion sites you need. Single-lumen sets like the SUB-109-G24 deliver to one site, while multi-needle configurations spread volume and speed absorption across the body — bi-furcated (SUB-260), tri-furcated (SUB-310, SUB-320), quad-furcated (SUB-400, SUB-410), and the penta-furcated SUB-509 for five simultaneous sites. Higher-volume SCIg regimens typically call for more sites to keep each infusion comfortable and well-tolerated.

Needle depth is the second decision. These sets are offered in 6 mm, 9 mm, and 12 mm lengths so you can match subcutaneous tissue thickness — shorter needles for leaner patients or pediatric use, longer needles where there's more subcutaneous fat. Gauge matters too: 27-gauge needles are the standard across most furcated sets, while 24-gauge options (SUB-212-G24, SUB-109-G24) accommodate more viscous medications or faster flow.

All sets feature 36-inch tubing (with a compact 3-1/2 inch option in the SUB-270), integrated site dressings for secure placement, and low priming volumes ranging from 0.14 mL to about 1 mL — important for minimizing medication waste. Sets are supplied without ports and without safety mechanisms, and the multi-site options are not made with natural rubber latex, an important consideration for sensitive patients.

Selecting an infusion set comes down to volume, viscosity, and patient anatomy. If you're unsure how many sites or what depth suits a given therapy, your prescribing clinician or pharmacy can confirm the specification before you order.