Zantac 360° Maximum Strength Antacid Tablets

If you've been reaching for heartburn relief and remembered the Zantac name, here's what changed: the reformulated Zantac 360° now uses famotidine, an H2 blocker, instead of the ranitidine found in older versions. That switch matters. Famotidine works by reducing the amount of acid your stomach produces, giving you relief that lasts longer than a chewable antacid that only neutralizes acid already present.

We carry Zantac 360° Maximum Strength Antacid Tablets in the 20 mg famotidine strength, packaged 50 per bottle. One tablet can prevent and relieve heartburn associated with acid indigestion and sour stomach brought on by eating or drinking certain foods and beverages. Because it can be taken proactively — up to 15 to 60 minutes before a meal you know tends to trigger symptoms — many people keep a bottle on hand specifically for those situations rather than waiting for discomfort to set in.

A common question we hear: is Zantac 360° safe now? Yes. Famotidine is a well-established, widely used acid reducer available over the counter, and it's the same active ingredient found in other trusted heartburn products. The maximum strength version delivers the higher 20 mg dose for stronger, all-day or all-night relief with a single tablet, versus stepping up from the lower-strength option.

The 50-count bottle is a practical size for anyone managing frequent heartburn or households that want a reliable supply without frequent reordering. Tablets are easy to swallow and don't require water, making them convenient to take at the table or on the go.

Explore the full Zantac 360° lineup to compare strengths and count sizes, and find the option that fits how often you need relief.