Zegerid OTC for Frequent Heartburn Relief

If frequent heartburn keeps interrupting your day — two or more times a week — Zegerid OTC is built for exactly that pattern. It pairs omeprazole, a proton pump inhibitor that reduces stomach acid at the source, with sodium bicarbonate that helps protect the omeprazole so it can start working. The result is a once-daily treatment course meant to keep heartburn from coming back, rather than just neutralizing acid after it flares.

We stock Zegerid OTC Antacid in both the standard package (11523726501) and the larger count (11523726503), so you can pick up a starter box or a full 14-day supply depending on how you use it.

A few things worth knowing before you buy. Zegerid OTC is a 14-day treatment taken once a day, in the morning at least an hour before eating — not an as-needed chewable for occasional indigestion. Most people notice full effect within one to four days, so it's normal not to feel relief on the very first dose. You shouldn't run more than one 14-day course every four months unless a doctor advises otherwise. Because it contains sodium bicarbonate, anyone on a low-sodium diet should factor that in.

Comparing acid-reducer options? Many shoppers weigh it against Prilosec OTC, another omeprazole-based PPI, before deciding which suits their routine. For antacids, gas relief, and other digestive-comfort items, browse our broader OTC Medications selection or the full Medications & OTC category to round out your medicine cabinet.