The Universal Thumb-O-Prene Support Brace provides a low-profile, custom fit that is both functional and comfortable. The unique design combines two stays, rigid and spiral, plus a movable elastic strap to address various pathologies of the thumb including tendonitis, basal joint arthritis and instability of the carpometacarpal (CMC) joint. The elastic strap may be wrapped between forefinger and thumb to help stabilize the CMC joint without restricting the use of the thumb or wrist. Universal fit allows the Universal Thumb-O-Prene Support Brace to be worn on either the left or right hand. One size fits most.