Gerber Good Start Soothe HM-O and Comforting Probiotics is designed to help with excessive crying, colic, and fussiness, and it is the first and only routine infant formula to have L. reuteri (a probiotic that has been clinically shown to reduce crying time by up to 50% in colicky breastfed babies in as little as one week). This unique formula is also made with a special carbohydrate blend (30% lactose) to ease fussiness and gas for infants with lactose intolerance as well as partially hydrolyzed 100% whey proteins broken down to be easy to digest which may help reduce the risk of atopic dermatitis (the most common allergic disease of infancy); they are called Comfort Proteins and are designed to help avoid spit-up, fussiness, and gas due to whole protein intolerance; plus, it includes expert-recommended DHA & ARA for brain and eye development.